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Contact

Highlighted Skills

Mass spectrometry
Ion mobility
Lipidomics
R
Excel
Liquid chromatography
Shiny
Python

Disclaimer

Made with the R package pagedown.

The source code is available on github.com/bsrose25/Rose-cv.

Last updated on 2022-05-17.

Main

Bailey S. Rose

Ph.D. Vanderbilt University

Education

Ph.D., Chemistry

Vanderbilt University

Nashville, TN

2022 - 2017

  • Dissertation: Improving Untargeted Molecular Annotation Using Structurally-Specific Ion Mobility-Mass Spectrometry
  • John A. McLean Research Group

B.S., Chemistry

Belmont University

Nashville, TN

2017 - 2013

  • Mathematics minor
  • Magna Cum Laude

Research Experience

Graduate Research Assistant

McLean Laboratory

Vanderbilt University

2022 - 2017

  • Explored strategies for improving lipid and metabolite identifications in untargeted -omics studies using ion mobility-derived collision cross sections (CCS). Developed standardization and reporting recommendations for CCS values derived from various types of ion mobility measurements and used these recommendations to build databases and implement novel algorithms for obtaining high-confidence molecular identifications. Other projects included LC-MS/MS method optimization for lipidomics and application of lipidomic methodology and data analysis pipelines to various biological systems in collaboration with the Center for Innovative Technology at Vanderbilt.

Undergraduate Researcher

Spence Laboratory

Belmont University

2017 - 2016

  • Alignment and completion of the optical set up of a cavity ring-down spectroscopy instrument.

Undergraduate Researcher

Stace Laboratory

Belmont University

2016 - 2015

  • Synthesis and characterization of an enzyme-mimic copper(II) Schiff-base complex. Exploration of the kinetics of its reaction with oxalic acid using spectroscopic methods.

Industry Experience

Analytical Chemist Summer Intern

Carlisle Construction Materials

Carlisle, PA

2016

  • Completed analytical projects relating to production quality control and warranty claims. Developed rheological methods and SOPs for new product lines in development, and trained staff on use and maintenance of the rheometer.

Teaching Experience

Graduate Teaching Assistant

Vanderbilt Chemistry Department

Nashville, TN

2021 - 2017

  • General Chemistry Lab, Analytical Chemistry Lab, and Capstone Advanced Integrated Lab

Publications

A Collision Cross Section Calibration Strategy for Lipid Measurements in SLIM-based High Resolution Ion Mobility

Rose, B. S.; May, J. C.; Reardon, A. R.; McLean, J. A.

N/A

2022

  • Journal of the American Society for Mass Spectrometry

Improving confidence in lipidomic annotations by incorporating empirical ion mobility regression analysis and chemical class prediction

Rose, B. S.; May, J. C.; Picache, J. A.; Codreanu, S. G.; Sherrod, S. D.; McLean, J. A.

N/A

2022

  • Bioinformatics
  • DOI: 10.1093/bioinformatics/btac197

High confidence shotgun lipidomics using structurally selective ion mobility-mass spectrometry

Rose, B. S.; Leaptrot, K. L.; Harris, R. A.; Sherrod, S. D.; May, J. C.; McLean, J. A.

N/A

2021

  • Shotgun Lipidomics: Methods and Protocols
  • DOI: 10.1007/978-1-0716-1410-5_2

Resolving Power and Collision Cross Section Measurement Accuracy of a Prototype High-Resolution Ion Mobility Platform Incorporating Structures for Lossless Ion Manipulation

May, J. C.; Leaptrot, K. L.; Rose, B. S.; Moser, K. L. M.; Deng, L.; Maxon, L.; DeBord, D.; McLean, J. A.

N/A

2021

  • Journal of the American Society for Mass Spectrometry
  • DOI: 10.1021/jasms.1c00056

Collision cross section compendium to filter and predict multi-omic compound identities.

Picache, J. A.; Rose, B. S.; Balinski, A.; Leaptrot, K. L.; Sherrod, S. D.; May, J. C.; McLean, J. A.

N/A

2019

  • Chemical Science
  • DOI: 10.1039/c8sc04396e

Untargeted molecular discovery in primary metabolism: collision cross section as a molecular descriptor in ion mobility-mass spectrometry

Nichols, C. M., Dodds, J. N.; Rose, B. S.; Picache, J. A., Morris, C. M.; May, J. C., Sherrod, S. D., McLean, J. A.

N/A

2018

  • Analytical Chemistry
  • DOI: 10.1021/acs.analchem.8b04322

Presentations

Structural Characterization of Previously Unresolved Lipids with HRIM-Mass Spectrometry

Rose, B. S., Reardon, A. R., Leaptrot, K. L., May, J. C., McLean, J. A.

N/A

2022

  • MOBILion Systems Technical Breakfast Seminar at ASMS. Minneapolis, MN
  • Invited oral presentation

Structural Characterization of Previously Unresolved Lipids with HRIM-Mass Spectrometry

Rose, B. S., Reardon, A. R., Leaptrot, K. L., May, J. C., McLean, J. A.

N/A

2022

  • 70th Annual Conference for the American Society of Mass Spectrometry and Allied Topics. Minneapolis, MN
  • Poster presentation

Lipid Collision Cross Section Calibration Strategies for High Resolution SLIM-based Traveling Wave Ion Mobility Separations

Rose, B. S., Leaptrot, K. L., Reardon, A. R., May, J. C., McLean, J. A.

N/A

2021

  • 69th Annual Conference for the American Society of Mass Spectrometry and Allied Topics. Philadelphia, PA
  • Poster presentation

Lipid Isomer Separations via a High Resolution Prototype SLIM-based Ion Mobility Instrument in Support of High Confidence Lipidomics

Leaptrot, K. L., Rose, B. S., Wormwood, K. L. M., May, J. C., McLean, J. A.

N/A

2020

  • VICB Student Research Symposium. Nashville, TN
  • Poster presentation

Collision cross section calibration strategies for a prototype SLIM-based ion mobility instrument

Rose, B. S., Leaptrot, K. L., Wormwood, K. L. M., May, J. C., McLean, J. A.

N/A

2020

  • Annual Conference for the American Society of Mass Spectrometry and Allied Topics “Reboot”
  • Poster presentation

Achieving a Consistent and Unified Community-wide Molecular Database: The Collision Cross Section Compendium

Rose, B. S., Picache, J. A., May, J. C., McLean, J. A.

N/A

2019

  • 1st Annual Agilent North American Ion Mobility Workshop. Raleigh, NC.
  • Invited oral presentation

Integrated multidimensional liquid chromatography-ion mobility-tandem mass spectrometry (LC-IM-MS/MS) workflow for high-confidence annotations in untargeted lipidomics

Rose, B. S.; Codreanu, S. G., May, J. C., Sherrod, S. D., McLean, J. A.

N/A

2019

  • 67th Annual Conference for the American Society of Mass Spectrometry and Allied Topics. Atlanta, GA.
  • Oral presentation

Development of a LC-IM-MS/MS workflow for high confidence lipidomics

Rose, B. S.; Codreanu, S. G.; May, J. C., Sherrod, S. D., McLean, J. A

N/A

2018

  • Southeastern Lipid Research Conference. Nashville, TN.
  • Poster presentation

Awards and recognition

ASMS Student Travel Award

American Society for Mass Spectrometry

N/A

2020

Student Travel Award

May Institute for Computational Statistics in Mass Spectrometry

N/A

2019

VICB Research Fellowship

Vanderbilt Institute of Chemical Biology

N/A

2018

Mitchum E. Warren Fellowship

Vanderbilt Chemistry Department

N/A

2017